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1

Microbiome data analysis with applications to pre-clinical studies using QIIME2: Statistical considerations

Rai, Shesh N., Qian, Chen, Pan, Jianmin, Rai, Jayesh P., Song, Ming, Bagaitkar, Juhi, Merchant, Michael, Cave, Matthew, Egilmez, Nejat K., McClain, Craig J.

Journal:

Genes & Diseases

Year:

2019

File:

PDF, 6.52 MB

2019

2

Defining genes that govern longevity in Caenorhabditis elegans

Robert H. Ebert II, Masood A. Shammas, Barbara H. Sohal, Rajindar S. Sohal, Nejat K. Egilmez, Scott Ruggles, Robert J. Shmookler Reis

Journal:

Year:

1996

Language:

english

File:

PDF, 1.31 MB

english, 1996

3

Consumption of the fish oil high-fat diet uncouples obesity and mammary tumor growth through induction of reactive oxygen species in pro-tumor macrophages

Liu, Lianliang, Jin, Rong, Hao, Jiaqing, Zeng, Jun, Yin, Di, Yi, Yanmei, Zhu, Mingming, Mandal, Anita, Hua, Yuan, Ng, Chin K., Egilmez, Nejat K, Sauter, Edward R., Li, Bing

Journal:

Cancer Research

Year:

2020

File:

PDF, 11.34 MB

2020

4

Interleukin-12 delivered by biodegradable microspheres promotes the antitumor activity of human peripheral blood lymphocytes in a human head and neck tumor xenograft/SCID mouse model

M. Abraham Kuriakose, F-A Chen, Nejat K. Egilmez, Y.S. Jong, Edith Mathiowitz, Mark D. DeLacure, Wesley L. Hicks Jr, Thom L. Loree, Richard B. Bankert

Journal:

Year:

2000

Language:

english

File:

PDF, 138 KB

english, 2000

5

Rapid release of cytoplasmic IL-15 from tumor-associated macrophages is an initial and critical event in IL-12-initiated tumor regression

Stephanie K. Watkins, Bing Li, Katharine S. Richardson, Kimberly Head, Nejat K. Egilmez, Qun Zeng, Jill Suttles, Robert D. Stout

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 493 KB

english, 2009

6

CD40-CD40 ligand (CD154) engagement is required but not sufficient for modulating MHC class I, ICAM-1 and Fas expression and proliferation of human non-small cell lung tumors

Makoto Yamada, Takashi Shiroko, Yoshihiro Kawaguchi, Yasuyuki Sugiyama, Nejat K. Egilmez, Fang-An Chen, Richard B. Bankert

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 560 KB

english, 2001

7

Strain evolution inCaenorhabditis elegans: Transposable elements as markers of interstrain evolutionary history

Nejat K. Egilmez, Robert H. Ebert, Robert J. Shmookler Reis

Journal:

Journal of Molecular Evolution

Year:

1995

Language:

english

File:

PDF, 1.29 MB

english, 1995

8

Tumor-Resident CD8+T-cell: The Critical Catalyst in IL-12-Mediated Reversal of Tumor Immune Suppression

Nejat K. Egilmez, Mehmet O. Kilinc

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Year:

2010

Language:

english

File:

PDF, 276 KB

english, 2010

9

CTLA-4 blockade augments human T lymphocyte-mediated suppression of lung tumor xenografts in SCID mice

Michael S. Sabel, Stephen D. Hess, Nejat K. Egilmez, Thomas F. Conway, Fang-An Chen, Richard B. Bankert

Journal:

Cancer Immunology, Immunotherapy

Year:

2005

Language:

english

File:

PDF, 352 KB

english, 2005

10

Transient activation of tumor-associated T-effector/memory cells promotes tumor eradication via NK-cell recruitment: minimal role for long-term T-cell immunity in cure of metastatic disease

Tao Gu, Mehmet O. Kilinc, Nejat K. Egilmez

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 433 KB

english, 2008

11

Nitric oxide short-circuits interleukin-12-mediated tumor regression

Nejat K. Egilmez, Jamie L. Harden, Lauren P. Virtuoso, Reto A. Schwendener, Mehmet O. Kilinc

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 439 KB

english, 2011

12

Antitumor efficacy of a human interleukin-12 expression plasmid demonstrated in a human peripheral blood leukocyte/human lung tumor xenograft SCID mouse model

Hess, Stephen D, Egilmez, Nejat K, Shiroko, Junko, Bankert, Richard B

Journal:

Cancer Gene Therapy

Year:

2001

Language:

english

File:

PDF, 212 KB

english, 2001

13

Intratumoral IL-12 and TNF-α–Loaded Microspheres Lead To Regression of Breast Cancer and Systemic Antitumor Immunity

Michael S. Sabel, Joseph Skitzki, Lloyd Stoolman, Nejat K. Egilmez, Edith Mathiowitz, Nicola Bailey, Wen-Jian Chang, Alfred E. Chang

Journal:

Annals of Surgical Oncology

Year:

2004

Language:

english

File:

PDF, 355 KB

english, 2004

14

Replication control and cellular life span

S. Michal Jazwinski, Nejat K. Egilmez, James B. Chen

Journal:

Experimental Gerontology

Year:

1989

Language:

english

File:

PDF, 932 KB

english, 1989

15

Growth of human tumor xenografts in SCID mice quantified using an immunoassay for tumor marker protein in serum

Thomas F Conway Jr., Michael S Sabel, Masahiko Sugano, John G Frelinger, Nejat K Egilmez, Fang-An Chen, Richard B Bankert

Journal:

Journal of Immunological Methods

Year:

2000

Language:

english

File:

PDF, 145 KB

english, 2000

16

An in-situ neoadjuvant vaccination with IL-12 and GM-CSF in biodegradable microspheres with systemic IL-2 provides protection against metastatic disease.

Hank C Hill, Michael Sabel, Nejat Egilmez, Richard B Bankert

Journal:

Journal of the American College of Surgeons

Year:

2000

Language:

english

File:

PDF, 177 KB

english, 2000

17

Evaluation and Optimization of Different Cationic Liposome Formulations forin VivoGene Transfer

Nejat K. Egilmez, Yoshimi Iwanuma, Richard B. Bankert

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 73 KB

english, 1996

18

Diverse Caenorhabditis elegans genes that are upregulated in dauer larvae also show elevated transcript levels in long-lived, aged, or starved adults

Vera Cherkasova, Srinivas Ayyadevara, Nejat Egilmez, Robert Shmookler Reis

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 419 KB

english, 2000

19

B cell tumor vaccine enhanced by covalent attachment of immunoglobulin to surface proteins on dendritic cells

Qiang Lou, Thomas F. Conway Jr., Nejat K. Egilmez, Jenni L. Loyall, Steven H. Bernstein, Raymond J. Kelleher Jr., Richard B. Bankert

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 365 KB

english, 2006

20

Human–SCID mouse chimeric models for the evaluation of anti-cancer therapies

Richard B Bankert, Nejat K Egilmez, Stephen D Hess

Journal:

Trends in Immunology

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

21

Neoadjuvant therapy with interleukin-12-loaded polylactic acid microspheres reduces local recurrence and distant metastases

Michael S. Sabel, Hank Hill, Yong S. Jong, Edith Mathiowitz, Richard B. Bankert, Nejat K. Egilmez

Journal:

Year:

2001

Language:

english

File:

PDF, 961 KB

english, 2001

22

Age-dependent somatic excision of transposable element Tc1 in Caernohabditis elegans

Nejat K. Egilmez, Robert J. Shmookler Reis

Journal:

Mutation Research/DNAging

Year:

1994

Language:

english

File:

PDF, 1.14 MB

english, 1994

23

Characterization of iNOS+Neutrophil-like ring cell in tumor-bearing mice

Lauren P Virtuoso, Jamie L Harden, Paula Sotomayor, Wade J Sigurdson, Fuminobu Yoshimura, Nejat K Egilmez, Boris Minev, Mehmet O Kilinc

Journal:

Journal of Translational Medicine

Year:

2012

Language:

english

File:

PDF, 500 KB

english, 2012

24

Indoleamine 2,3-Dioxygenase and Dendritic Cell Tolerogenicity

Harden, Jamie L, Egilmez, Nejat K

Journal:

Immunological Investigations

Year:

2012

Language:

english

File:

PDF, 569 KB

english, 2012

25

Mo1919 Effect of Directly Injecting Cytokine-Containing Microbeads on a Endoscopically Initiated Model of Colon Cancer

Dryden, Gerald W., Vanchinathan, Shunmugavadivoo, Suttles, Jill, Egilmez, Nejat K.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 128 KB

english, 2014

26

Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors

Gerber, Scott A., Lim, Joanne Y.H., Connolly, Kelli A., Sedlacek, Abigail L., Barlow, Margaret L., Murphy, Shawn P., Egilmez, Nejat K., Lord, Edith M.

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 4.29 MB

english, 2014

27

Characterization of Cytokine-Encapsulated Controlled-Release Microsphere Adjuvants

Sharma, Atima, Harper, Carl M., Hammer, Laura, Nair, Raji E., Mathiowitz, Edith, Egilmez, Nejat K.

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

2004

Language:

english

File:

PDF, 133 KB

english, 2004

28

Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis

Deng, Zhongbin, Mu, Jingyao, Tseng, Michael, Wattenberg, Binks, Zhuang, Xiaoying, Egilmez, Nejat K., Wang, Qilong, Zhang, Lifeng, Norris, James, Guo, Haixun, Yan, Jun, Haribabu, Bodduluri, Miller, Don

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 4.83 MB

english, 2015

29

Oral Delivery of Particulate Transforming Growth Factor Beta 1 and All-Trans Retinoic Acid Reduces Gut Inflammation in Murine Models of Inflammatory Bowel Disease

Conway, Thomas F., Hammer, Laura, Furtado, Stacia, Mathiowitz, Edith, Nicoletti, Ferdinando, Mangano, Katia, Egilmez, Nejat K., Auci, Dominick L.

Journal:

Journal of Crohn's and Colitis

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

30

Tumor Escape and Progression under Immune Pressure

Manjili, Masoud H., Egilmez, Nejat, Knutson, Keith L., Selvan, Senthamil R., Ostberg, Julie R.

Journal:

Clinical & Developmental Immunology

Year:

2012

Language:

english

File:

PDF, 49 KB

english, 2012

31

Modulating gut immunity and neoplasia with oral cytokine adjuvants

Ozbilge, Hatice, LeVea, Charles, Chung, Allen Y, Li, Qingsheng, Egilmez, Nejat K

Journal:

Year:

2015

Language:

english

File:

PDF, 232 KB

english, 2015

32

[Methods in Enzymology] Liposomes, Part C Volume 373 || Liposome-Mediated Cytokine Gene Delivery to Human Tumor Xenografts

Eğilmez, Nejat K

Year:

2003

Language:

english

File:

PDF, 83 KB

english, 2003

33

Chemoimmunotherapy as long-term maintenance therapy for cancer

Egilmez, Nejat K., Harden, Jamie L., Rowswell-Turner, Rachael B.

Journal:

Year:

2012

Language:

english

File:

PDF, 674 KB

english, 2012

34

Regression of Established Autochthonous Mammary Tumors and Induction of Systemic Anti-Tumor T- and B-Cell Immunity in HER-2/NEU Transgenic Mice after Treatment with IL-12 and GM-CSF-Encapsulated Microspheres

Nair, Easwari R, Jong, Yong S, Egilmez, Nejat K

Journal:

Journal of Immunotherapy

Year:

2004

Language:

english

File:

PDF, 48 KB

english, 2004

35

Cytokines Delivered by Biodegradable Microspheres Promote Effective Suppression of Human Tumors by Human Peripheral Blood Lymphocytes in the SCID???Winn Model

Egilmez, Nejat K., Jong, Yong S., Hess, Stephen D., Jacob, Jules S., Mathiowitz, Edith, Bankert, Richard B.

Journal:

Journal of Immunotherapy

Year:

2000

Language:

english

File:

PDF, 138 KB

english, 2000

36

Human Inflammatory Cells Within the Tumor Microenvironment of Lung Tumor Xenografts Mediate Tumor Growth Suppression in Situ that Depends on and Is Augmented by Interleukin-12

Sugiyama, Yasuyuki, Kato, Motohisa, Chen, Fang-An, Williams, Scott S., Kawaguchi, Yoshihiro, Miya, Kiichi, Jong, Yong S., Mathiowitz, Edith, Egilmez, Nejat K., Bankert, Richard B.

Journal:

Journal of Immunotherapy

Year:

2001

Language:

english

File:

PDF, 1.12 MB

english, 2001

37

Controlled-release Particulate Cytokine Adjuvants for Cancer Therapy

Egilmez, Nejat, Kilinc, Mehmet, Gu, Tao, Conway, Thomas

Journal:

Endocrine Metabolic & Immune Disorders - Drug Targets

Year:

2007

Language:

english

File:

PDF, 117 KB

english, 2007

38

Intra-Tumoral IL-12 + GM-CSF Microsphere Therapy Induces Activation of Tumor-Associated T-Effector/Memory Cells, Exodus of CD4+ CD25+ T-Suppressors and Infiltration of CD8+ T-Effectors

Kilinc, Okyay M, Aulakh, Karanvir S, Nair, Raji E, Jones, Stacy A, Alard, Pascale, Kosiewicz, Michele M, Egilmez, Nejat K

Journal:

Journal of Immunotherapy

Year:

2005

Language:

english

File:

PDF, 1.45 MB

english, 2005

39

IL-12 + GM-CSF Microsphere Therapy Induces Eradication of Advanced Spontaneous Tumors in her-2/neu Transgenic Mice But Fails to Achieve Long-Term Cure Due to the Inability to Maintain Effector T-Cell Activity

Nair, Raji E, Jong, Yong S, Jones, Stacy A, Sharma, Atima, Mathiowitz, Edith, Egilmez, Nejat K

Journal:

Journal of Immunotherapy

Year:

2006

Language:

english

File:

PDF, 874 KB

english, 2006

40

Ontogeny of Tumor-associated CD4+CD25+Foxp3+ T-regulatory Cells

Li, Qingsheng, Egilmez, Nejat K.

Journal:

Immunological Investigations

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

41

Corrigendum: Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis

Deng, Zhongbin, Mu, Jingyao, Tseng, Michael, Wattenberg, Binks, Zhuang, Xiaoying, Egilmez, Nejat K., Wang, Qilong, Zhang, Lifeng, Norris, James, Guo, Haixun, Yan, Jun, Haribabu, Bodduluri, Miller, Don

Journal:

Nature Communications

Year:

2016

File:

PDF, 76 KB

2016

42

Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenicCD4 + T-cells and induction of antitumor CD8 + T-cell activity

Gu, Tao, De Jesus, Magdia, Gallagher, Heather C., Burris, Thomas P., Egilmez, Nejat K.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

43

Expression of adipocyte/macrophage fatty acid binding protein in tumor associated macrophages promotes breast cancer progression

Hao, Jiaqing, Yan, Fei, Zhang, Yuwen, Triplett, Ashley, Zhang, Ying, Schultz, Debra A., Sun, Yanwen, Zeng, Jun, Silverstein, Kevin A.T., Zheng, Qi, Bernlohr, David A, Cleary, Margot P., Egilmez, Nejat

Journal:

Cancer Research

Year:

2018

Language:

english

File:

PDF, 2.94 MB

english, 2018

44

Intravaginal Administration of Interleukin 12 during Genital Gonococcal Infection in Mice Induces Immunity to Heterologous Strains of Neisseria gonorrhoeae

Liu, Yingru, Perez, Julianny, Hammer, Laura A., Gallagher, Heather C., De Jesus, Magdia, Egilmez, Nejat K., Russell, Michael W., Pascual, David W.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.14 MB

english, 2018

45

Protective Potential of Antioxidant Enzymes as Vaccines for Schistosomiasis in a Non-Human Primate Model

Carvalho-Queiroz, Claudia, Nyakundi, Ruth, Ogongo, Paul, Rikoi, Hitler, Egilmez, Nejat K., Farah, Idle O., Kariuki, Thomas M., LoVerde, Philip T.

Journal:

Frontiers in Immunology

Year:

2015

Language:

english

File:

PDF, 14.15 MB

english, 2015

46

Circulating Adipose Fatty Acid Binding Protein Is a New Link Underlying Obesity-Associated Breast/Mammary Tumor Development

Hao, Jiaqing, Zhang, Yuwen, Yan, Xiaofang, Yan, Fei, Sun, Yanwen, Zeng, Jun, Waigel, Sabine, Yin, Yanhui, Fraig, Mostafa M., Egilmez, Nejat K., Suttles, Jill, Kong, Maiying, Liu, Shujun, Cleary, Margo

Journal:

Cell Metabolism

Year:

2018

Language:

english

File:

PDF, 4.33 MB

english, 2018

47

Inhaled IL-10 Suppresses Lung Tumorigenesis via Abrogation of Inflammatory Macrophage–Th17 Cell Axis

Li, Qingsheng, Anderson, Charles D., Egilmez, Nejat K.

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

48

Enhanced gut barrier integrity sensitizes colon cancer to immune therapy

Bhutiani, Neal, Li, Qingsheng, Anderson, Charles D., Gallagher, Heather C., De Jesus, Magdia, Singh, Rajbir, Jala, Venkatkrishna R., Fraig, Mostafa, Gu, Tao, Egilmez, Nejat K.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.96 MB

english, 2018

49

A Novel Form of 4-1BBL Prevents Cancer Development via Nonspecific Activation of CD4 + T and Natural Killer Cells

Barsoumian, Hampartsoum B., Batra, Lalit, Shrestha, Pradeep, Bowen, William S., Zhao, Hong, Egilmez, Nejat K., Gomez-Gutierrez, Jorge G., Yolcu, Esma S., Shirwan, Haval

Journal:

Cancer Research

Year:

2019

Language:

english

File:

PDF, 1.55 MB

english, 2019

50

Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death

Rao, Enyu, Zhang, Yuwen, Zhu, Ganqian, Hao, Jiaqing, Persson, Xuan-Mai T., Egilmez, Nejat K., Suttles, Jill, Li, Bing

Journal:

Year:

2015

Language:

english

File:

PDF, 5.34 MB

english, 2015